Case Title: Flame cells in Multiple Myeloma Category: Multiple myeloma and related plasma cell neoplasm Author(s): Dr. Bassam Francis Matti, MD, Consultant hematologist; Dr. Zahraa Akram Thabit, Hematopathologist Case Description: Flame Cells: these are plasma cells with vermillion-staining glycogen-rich overstuffed fibrils. Although these cytoplasmic features are suggestive of neoplastic plasma cells, they can also be found in reactive cells as well. They are also thought to be heavily associated with IgA myelomas, however they can also be associated with IgG, and IgM myeloma. Date : 2024-06-22 Submitted By : Dr. Zahraa Akram Thabit
Case Title: Flame cells in Multiple Myeloma Category: Multiple myeloma and related plasma cell neoplasm Author(s): Dr. Bassam Francis Matti, MD, Consultant hematologist; Dr. Zahraa Akram Thabit, Hematopathologist Case Description: Flame Cells: these are plasma cells with vermillion-staining glycogen-rich overstuffed fibrils. Although these cytoplasmic features are suggestive of neoplastic plasma cells, they can also be found in reactive cells as well. They are also thought to be heavily associated with IgA myelomas, however they can also be associated with IgG, and IgM myeloma. Date : 2024-06-22 Submitted By : Dr. Zahraa Akram Thabit